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DRUG & NUTRIENT INTERACTIONS Dr.Janaki.B, Nutritionist WHY ? As treatment for many diseases becomes increasingly complex with multiple drug therapies scheduled at varying times, the need to identify clinically significant DNIs is an essential part of medication management. This is a shared responsibility between health care professionals to interpret available data and individualize an approach to therapy that is compatible with the patient’s disease state, life stage, and dietary intake. Although the influence of nutrition on health is obvious, its critical role in the care of patients is not as widely recognized. In caring for patients, more attention is often paid to the role of drug therapy. The field of clinical nutrition actually overlaps with the field of pharmacotherapy at several points, but none more clearly than at the interaction of drug and nutrient. A drug–nutrient interaction is considered the result of a physical, chemical, physiologic, or pathophysiologic relationship between a drug and nutrient(s)/food that is deemed significant when the therapeutic response is altered or the nutritional status compromised.
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